Hypertonicity: Pathophysiologic Concept and Experimental Studies

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Hypertonicity: Pathophysiologic Concept and Experimental Studies

Disturbances in tonicity (effective osmolarity) are the major clinical disorders affecting cell volume. Cell shrinking secondary to hypertonicity causes severe clinical manifestations and even death. Quantitative management of hypertonic disorders is based on formulas computing the volume of hypotonic fluids required to correct a given level of hypertonicity. These formulas have limitations. Th...

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ژورنال

عنوان ژورنال: Cureus

سال: 2016

ISSN: 2168-8184

DOI: 10.7759/cureus.596